Clinical diagnosis of oral submucous fibrosis with optical coherence tomography

Cheng Kuang Lee, Meng Tsan Tsai, C. C. Yang, Chun Pin Chiang

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

A swept-source optical coherence tomography (SS-OCT) system with a specially designed probe is built for clinical scanning of oral submucous fibrosis (OSF) patients. By analysing 44 OSF cases of SS-OCT scanning results, two indicators, including epithelium (EP) thickness and standard deviation (SD) of A-mode scan intensity in the laminar propria (LP) layer, are found useful for real-time OSF diagnosis. Statistics show that sensitivity and specificity of LP SD can reach 84.1 and 95.5 %, respectively. Also, both sensitivity and specificity of EP thickness can reach 100 %.

Original languageEnglish
Title of host publicationOptical Sensors and Biophotonics
DOIs
StatePublished - 2009
Externally publishedYes
EventOptical Sensors and Biophotonics - Shanghai, China
Duration: 2 Nov 20096 Nov 2009

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume7634
ISSN (Print)0277-786X

Conference

ConferenceOptical Sensors and Biophotonics
Country/TerritoryChina
CityShanghai
Period2/11/096/11/09

Keywords

  • Medical and biological imaging
  • Optical coherence tomography
  • Oral submucous fibrosis

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