Projects per year
Personal profile
Education
1989/09-1996/06 Ph.D., National Yang-Ming University, Taipei, Republic of China
1985/09-1989/06 B.S., China Medical University, Taichung, Republic of China
1985/09-1989/06 B.S., China Medical University, Taichung, Republic of China
Professional Information
2009-present Professor, Department of Molecular Biology and Human Genetics, Tzu-Chi University, Hualien, Taiwan.
2009-present Professor, Ph. D. Program, Institute of Medical Sciences, TCU.
2013-2017 Dean College of Life Science (CLS), TCU, Taiwan.
2009-2017 Chair, Department of Molecular Biology and Human Genetics, CLS/TCU
2008-2016 Join-appointed Professor of Nano-Research Center, National Donghwa University, Hualien, Taiwan
2001-2008 Assistant/Associate Professor, Department of Molecular Biology and Human Genetics, Tzu-Chi University, Hualien, Taiwan
1999-2001 Postdoctoral fellow, Yale University, USA
2009-present Professor, Ph. D. Program, Institute of Medical Sciences, TCU.
2013-2017 Dean College of Life Science (CLS), TCU, Taiwan.
2009-2017 Chair, Department of Molecular Biology and Human Genetics, CLS/TCU
2008-2016 Join-appointed Professor of Nano-Research Center, National Donghwa University, Hualien, Taiwan
2001-2008 Assistant/Associate Professor, Department of Molecular Biology and Human Genetics, Tzu-Chi University, Hualien, Taiwan
1999-2001 Postdoctoral fellow, Yale University, USA
Award
2013- present, Study Sections/Review Committee Member, National Science and Technology Council, R.O.C.
2010- present, The National Science Council subsidizes colleges and universities to recruit special talents award
2022 The International Inventor Prize, Guo-Guang Awarding Medal, Taiwan International invention Award Winners Association
2022 Excellent Research Award, Tzu-Chi University
2002-2022 (except 4 years) Research Paper Award, Tzu-Chi University
2011 Research Excellence Award, Tzu-Chi University
2010- present, The National Science Council subsidizes colleges and universities to recruit special talents award
2022 The International Inventor Prize, Guo-Guang Awarding Medal, Taiwan International invention Award Winners Association
2022 Excellent Research Award, Tzu-Chi University
2002-2022 (except 4 years) Research Paper Award, Tzu-Chi University
2011 Research Excellence Award, Tzu-Chi University
Research Interests
Injury cell specific drug delivery system
Drug delivery system across blood–brain barrier
Immune checkpoint and repair checkpoint
Exosome-mediated regulation in health and diseases
Regulated cell death in health and diseases
Metabolic regulation in health and diseases
Psychological and neurological stresses-induced diseases
Blood cell
Stem cells in regenerative medicine
Cancers and anti-cancer drugs
Nanomaterials
Nanomedicine
Nanodiamonds
Anti-bacterial materials
Pathogen-host interactions
Dengue and dengue hemorrhage fever
Drug delivery system across blood–brain barrier
Immune checkpoint and repair checkpoint
Exosome-mediated regulation in health and diseases
Regulated cell death in health and diseases
Metabolic regulation in health and diseases
Psychological and neurological stresses-induced diseases
Blood cell
Stem cells in regenerative medicine
Cancers and anti-cancer drugs
Nanomaterials
Nanomedicine
Nanodiamonds
Anti-bacterial materials
Pathogen-host interactions
Dengue and dengue hemorrhage fever
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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國科會: Targeted Drug Delivery to Dying Cells: A Novel Approach to Treat Inflammatory Bowel Disease
Chang, H.-H. (PI)
1/08/25 → 31/07/26
Project: Research Project › A.Government Departments > a.National Science and Technology Council
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國科會: Biogenesis and regulatory mechanism of dengue virus-induced proinflammatory platelet extracellular vesicles(3/3)
Chang, H.-H. (PI)
1/08/24 → 31/07/25
Project: Research Project › A.Government Departments > a.National Science and Technology Council
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慈濟醫療志業: 衣康酸依賴性及非衣康酸依賴性ATF/NRF2途徑調節在抗發炎和組織修復中的作用(3/3)
Chang, H.-H. (PI)
1/01/24 → 31/12/24
Project: Research Project › C.Other Units
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慈濟醫療志業: P-選擇素和ATF3 依賴性的血小板-上皮細胞調節在束縛誘發的心理壓力下所造成胃腸損傷的保護機制(1/3)
Chang, H.-H. (PI)
1/01/24 → 31/12/24
Project: Research Project › C.Other Units
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國科會: Biogenesis and regulatory mechanism of dengue virus-induced proinflammatory platelet extracellular vesicles(2/3)
Chang, H.-H. (PI)
1/08/23 → 31/07/24
Project: Research Project › A.Government Departments > a.National Science and Technology Council
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Virus-Induced Pathogenic Antibodies: Lessons from Long COVID and Dengue Hemorrhage Fever
Sun, D. S., Lien, T. S. & Chang, H. H., Mar 2025, In: International Journal of Molecular Sciences. 26, 5, 1898.Research output: Contribution to journal › Review article › peer-review
Open Access5 Scopus citations -
Berberine mediated fluorescent gold nanoclusters in biomimetic erythrocyte ghosts as a nanocarrier for enhanced photodynamic treatment
Pearl, W. G., Selvam, R., Karmenyan, A. V., Perevedentseva, E. V., Hung, S. C., Chang, H. H., Shushunova, N., Prikhozhdenko, E. S., Bratashov, D., Tuchin, V. V. & Cheng, C. L., 19 Jan 2024, In: RSC Advances. 14, 5, p. 3321-3334 14 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Dachshund Homolog 1: Unveiling Its Potential Role in Megakaryopoiesis and Bacillus anthracis Lethal Toxin-Induced Thrombocytopenia
Lin, G. L., Chang, H. H., Lin, W. T., Liou, Y. S., Lai, Y. L., Hsieh, M. H., Chen, P. K., Liao, C. Y., Tsai, C. C., Wang, T. F., Chu, S. C., Kau, J. H., Huang, H. H., Hsu, H. L. & Sun, D. S., Mar 2024, In: International Journal of Molecular Sciences. 25, 6, 3102.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Dengue Envelope Protein as a Cytotoxic Factor Inducing Hemorrhage and Endothelial Cell Death in Mice
Lien, T. S., Sun, D. S., Wu, W. S. & Chang, H. H., Oct 2024, In: International Journal of Molecular Sciences. 25, 19, 10858.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Editorial: Regulated cell death pathways in the initiation and reversal of inflammation and tissue repair
Chang, H. H., 2024, In: Frontiers in Immunology. 15, 1367215.Research output: Contribution to journal › Editorial
Open Access